Androgen Receptor and MicroRNA-21 axis down-regulates transforming growth factor beta receptor II (TGFBR2) expression in Prostate Cancer

Prostate cancer cells escape growth inhibition from TGFβ by down-regulating TGFβ receptors. However, the mechanism by which cancer cells down-regulate TGFβ receptors in prostate is not clear. Here, we showed that coordinated action of miR-21 and androgen receptor (AR) signaling played a critical rol...

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Hlavní autoři: Mishra, Sweta, Deng, Janice J., Gowda, Pramod S., Rao, Manjeet K., Lin, Chun-Lin, Chen, Chun Liang, Huang, Tim, Sun, Lu-Zhe
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962713/
https://ncbi.nlm.nih.gov/pubmed/24037531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.374
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