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Androgen receptor primes prostate cancer cells to apoptosis through down-regulation of basal p21 expression

The androgen receptor (AR) for the male hormone androgen plays an important role in regulation of cell survival or death depending on the nature of cellular context and extracellular stimuli. The pro-survival function of AR is mediated mainly by transcriptional regulation of its target genes. By con...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: Lin, Yuting, Lu, Ziyan, Kokontis, John, Xiang, Jialing
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5702546/
https://ncbi.nlm.nih.gov/pubmed/23159636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.10.135
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