Endogenous fructose production and metabolism in the liver contributes to the development of metabolic syndrome

Carbohydrates with high glycemic index are proposed to promote the development of obesity, insulin resistance and fatty liver, but the mechanism by which this occurs remains unknown. High serum glucose concentrations glucose are known to induce the polyol pathway and increase fructose generation in...

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Main Authors: Lanaspa, Miguel A, Ishimoto, Takuji, Li, Nanxing, Cicerchi, Christina, Orlicky, David J., Ruzicky, Philip, Rivard, Christopher, Inaba, Shinichiro, Roncal-Jimenez, Carlos A., Bales, Elise S., Diggle, Christine P., Asipu, Aruna, Petrash, J. Mark, Kosugi, Tomoki, Maruyama, Shoichi, Sanchez-Lozada, Laura G., McManaman, James L., Bonthron, David T, Sautin, Yuri Y., Johnson, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3833672/
https://ncbi.nlm.nih.gov/pubmed/24022321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3434
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