Accelerated homologous recombination and subsequent genome modification in Drosophila

Gene targeting by ‘ends-out’ homologous recombination enables the deletion of genomic sequences and concurrent introduction of exogenous DNA with base-pair precision without sequence constraint. In Drosophila, this powerful technique has remained laborious and hence seldom implemented. We describe a...

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Detaylı Bibliyografya
Asıl Yazarlar: Baena-Lopez, Luis Alberto, Alexandre, Cyrille, Mitchell, Alice, Pasakarnis, Laurynas, Vincent, Jean-Paul
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Company of Biologists 2013
Konular:
Techniques and Resources
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3833436/
https://ncbi.nlm.nih.gov/pubmed/24154526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.100933
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