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Accelerated homologous recombination and subsequent genome modification in Drosophila
Gene targeting by ‘ends-out’ homologous recombination enables the deletion of genomic sequences and concurrent introduction of exogenous DNA with base-pair precision without sequence constraint. In Drosophila, this powerful technique has remained laborious and hence seldom implemented. We describe a...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Company of Biologists
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3833436/ https://ncbi.nlm.nih.gov/pubmed/24154526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.100933 |
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