Oral clopidogrel improves cutaneous microvascular function through EDHF-dependent mechanisms in middle-aged humans

Platelet P(2)Y(12)-ADP and COX-1 receptor inhibition with oral clopidogrel (CLO) and low-dose aspirin (ASA), respectively, attenuates reflex-mediated cutaneous vasodilation, but little is known about how these medications affect local vasodilatory signaling. Reactive hyperemia (RH) results in vasodi...

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Bibliographische Detailangaben
Hauptverfasser: Dahmus, Jessica D., Bruning, Rebecca S., Larry Kenney, W., Alexander, Lacy M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2013
Schlagworte:
Cardiovascular and Renal Integration
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3833399/
https://ncbi.nlm.nih.gov/pubmed/23804278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00366.2012
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