Oral atorvastatin therapy restores cutaneous microvascular function by decreasing arginase activity in hypercholesterolaemic humans

ABSTRACT: Elevated low-density lipoproteins (LDLs) are associated with vascular dysfunction evident in the cutaneous microvasculature. We hypothesized that uncoupled endothelial nitric oxide synthase (NOS3) through upregulated arginase contributes to cutaneous microvascular dysfunction in hyperochol...

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Detaylı Bibliyografya
Asıl Yazarlar: Holowatz, Lacy A, Santhanam, Lakshmi, Webb, Alanah, Berkowitz, Dan E, Kenney, W Larry
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Science Inc 2011
Konular:
Integrative
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3090606/
https://ncbi.nlm.nih.gov/pubmed/21486801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.203935
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