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Up-regulation of arginase activity contributes to attenuated reflex cutaneous vasodilatation in hypertensive humans
Reflex cutaneous vasodilatation is dependent on nitric oxide (NO), which is diminished in hypertension (HTN). Arginase may be up-regulated with HTN, which preferentially metabolizes l-arginine (l-arg), competing with NO-synthase (NOS)-mediated pathways and limiting NO synthesis. We hypothesized that...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2075195/ https://ncbi.nlm.nih.gov/pubmed/17347269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.128959 |
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