Oral atorvastatin therapy restores cutaneous microvascular function by decreasing arginase activity in hypercholesterolaemic humans

ABSTRACT: Elevated low-density lipoproteins (LDLs) are associated with vascular dysfunction evident in the cutaneous microvasculature. We hypothesized that uncoupled endothelial nitric oxide synthase (NOS3) through upregulated arginase contributes to cutaneous microvascular dysfunction in hyperochol...

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Библиографические подробности
Главные авторы: Holowatz, Lacy A, Santhanam, Lakshmi, Webb, Alanah, Berkowitz, Dan E, Kenney, W Larry
Формат: Artigo
Язык:Inglês
Опубликовано: Blackwell Science Inc 2011
Предметы:
Integrative
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3090606/
https://ncbi.nlm.nih.gov/pubmed/21486801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.203935
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