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mTOR signaling in liver regeneration: Rapamycin combined with growth factor treatment

AIM: To investigate the effects of mammalian target of rapamycin (mTOR) inhibition on liver regeneration and autophagy in a surgical resection model. METHODS: C57BL/6 mice were subjected to a 70% partial hepatectomy (PH) and treated intraperitoneally every 24 h with a combination of the mTOR inhibit...

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Detalhes bibliográficos
Main Authors: Fouraschen, Suomi MG, de Ruiter, Petra E, Kwekkeboom, Jaap, de Bruin, Ron WF, Kazemier, Geert, Metselaar, Herold J, Tilanus, Hugo W, van der Laan, Luc JW, de Jonge, Jeroen
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Co., Limited 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3832859/
https://ncbi.nlm.nih.gov/pubmed/24255881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5500/wjt.v3.i3.36
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