Influence of the CXCL1 rs4074 A Allele on Alcohol Induced Cirrhosis and HCC in Patients of European Descent

BACKGROUND AND AIMS: CXCL1 (CXC chemokine-ligand-1) is a ligand for CXC chemokine receptor 2 expressed on hepatic stellate cells (HSC). Thus, CXCL1 might contribute to HSC activation and fibrogenesis. In the present study, we investigated the influence of the CXCL1 rs4074 polymorphism on the occurre...

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Main Authors: Nischalke, Hans Dieter, Berger, Cordula, Lutz, Philipp, Langhans, Bettina, Wolter, Franziska, Eisenhardt, Marianne, Krämer, Benjamin, Kokordelis, Pavlos, Glässner, Andreas, Müller, Tobias, Rosendahl, Jonas, Fischer, Janett, Berg, Thomas, Grünhage, Frank, Leifeld, Ludger, Soyka, Michael, Nattermann, Jacob, Sauerbruch, Tilman, Stickel, Felix, Spengler, Ulrich
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3832473/
https://ncbi.nlm.nih.gov/pubmed/24260493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080848
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