The HLA-A2 Restricted T Cell Epitope HCV Core(35–44) Stabilizes HLA-E Expression and Inhibits Cytolysis Mediated by Natural Killer Cells

Impaired activity of natural killer cells has been proposed as a mechanism contributing to viral persistence in hepatitis C virus (HCV) infection. Natural cytotoxicity is regulated by interactions of HLA-E with inhibitory CD94/NKG2A receptors on natural killer (NK) cells. Here, we studied whether HC...

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Main Authors: Nattermann, Jacob, Nischalke, Hans Dieter, Hofmeister, Valeska, Ahlenstiel, Golo, Zimmermann, Henning, Leifeld, Ludger, Weiss, Elisabeth H., Sauerbruch, Tilman, Spengler, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2005
Assuntos:
Original Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602324/
https://ncbi.nlm.nih.gov/pubmed/15681828
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