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Ribavirin Exerts Differential Effects on Functions of Cd4(+) Th1, Th2, and Regulatory T Cell Clones in Hepatitis C

Ribavirin improves outcomes of therapy in chronic hepatitis C but its mode of action has still remained unclear. Since ribavirin has been proposed to modulate the host’s T cell responses, we studied its direct effects on CD4(+) T cell clones with diverse functional polarization which had been genera...

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Detalhes bibliográficos
Main Authors: Langhans, Bettina, Nischalke, Hans Dieter, Arndt, Simone, Braunschweiger, Ingrid, Nattermann, Jacob, Sauerbruch, Tilman, Spengler, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407113/
https://ncbi.nlm.nih.gov/pubmed/22848715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042094
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