TRAIL receptor I (DR4) polymorphisms C626G and A683C are associated with an increased risk for hepatocellular carcinoma (HCC) in HCV-infected patients

BACKGROUND: Tumour surveillance via induction of TRAIL-mediated apoptosis is a key mechanism, how the immune system prevents malignancy. To determine if gene variants in the TRAIL receptor I (DR4) gene affect the risk of hepatitis C virus (HCV)-induced liver cancer (HCC), we analysed DR4 mutations C...

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Detalhes bibliográficos
Main Authors: Körner, Christian, Riesner, Katarina, Krämer, Benjamin, Eisenhardt, Marianne, Glässner, Andreas, Wolter, Franziska, Berg, Thomas, Müller, Tobias, Sauerbruch, Tilman, Nattermann, Jacob, Spengler, Ulrich, Nischalke, Hans Dieter
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372437/
https://ncbi.nlm.nih.gov/pubmed/22401174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-85
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