Sleeping Beauty mutagenesis in a mouse medulloblastoma model defines networks that discriminate between human molecular subgroups

The Sleeping Beauty (SB) transposon mutagenesis screen is a powerful tool to facilitate the discovery of cancer genes that drive tumorigenesis in mouse models. In this study, we sought to identify genes that functionally cooperate with sonic hedgehog signaling to initiate medulloblastoma (MB), a tum...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Genovesi, Laura A., Ng, Ching Ging, Davis, Melissa J., Remke, Marc, Taylor, Michael D., Adams, David J., Rust, Alistair G., Ward, Jerrold M., Ban, Kenneth H., Jenkins, Nancy A., Copeland, Neal G., Wainwright, Brandon J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2013
Pynciau:
PNAS Plus
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3832011/
https://ncbi.nlm.nih.gov/pubmed/24167280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1318639110
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