Gata3/Ruvbl2 complex regulates T helper 2 cell proliferation via repression of Cdkn2c expression

GATA-binding protein 3 (Gata3) controls the differentiation of naive CD4 T cells into T helper 2 (Th2) cells by induction of chromatin remodeling of the Th2 cytokine gene loci, direct transactivation of Il5 and Il13 genes, and inhibition of Ifng. Gata3 also facilitates Th2 cell proliferation via add...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hosokawa, Hiroyuki, Tanaka, Tomoaki, Kato, Miki, Shinoda, Kenta, Tohyama, Hiroyuki, Hanazawa, Asami, Tamaki, Yuuki, Hirahara, Kiyoshi, Yagi, Ryoji, Sakikawa, Ikue, Morita, Atsushi, Nagira, Morio, Poyurovsky, Masha V., Suzuki, Yutaka, Motohashi, Shinichiro, Nakayama, Toshinori
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2013
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3832009/
https://ncbi.nlm.nih.gov/pubmed/24167278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1311100110
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