Gata3/Ruvbl2 complex regulates T helper 2 cell proliferation via repression of Cdkn2c expression

GATA-binding protein 3 (Gata3) controls the differentiation of naive CD4 T cells into T helper 2 (Th2) cells by induction of chromatin remodeling of the Th2 cytokine gene loci, direct transactivation of Il5 and Il13 genes, and inhibition of Ifng. Gata3 also facilitates Th2 cell proliferation via add...

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Detalhes bibliográficos
Main Authors: Hosokawa, Hiroyuki, Tanaka, Tomoaki, Kato, Miki, Shinoda, Kenta, Tohyama, Hiroyuki, Hanazawa, Asami, Tamaki, Yuuki, Hirahara, Kiyoshi, Yagi, Ryoji, Sakikawa, Ikue, Morita, Atsushi, Nagira, Morio, Poyurovsky, Masha V., Suzuki, Yutaka, Motohashi, Shinichiro, Nakayama, Toshinori
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3832009/
https://ncbi.nlm.nih.gov/pubmed/24167278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1311100110
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