Intracellular pH reduction prevents excitotoxic and ischemic neuronal death by inhibiting NADPH oxidase

Sustained activation of N-methyl-d-aspartate (NMDA) -type glutamate receptors leads to excitotoxic neuronal death in stroke, brain trauma, and neurodegenerative disorders. Superoxide production by NADPH oxidase is a requisite event in the process leading from NMDA receptor activation to excitotoxic...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Lam, Tina I., Brennan-Minnella, Angela M., Won, Seok Joon, Shen, Yiguo, Hefner, Colleen, Shi, Yejie, Sun, Dandan, Swanson, Raymond A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2013
Soggetti:
PNAS Plus
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3832003/
https://ncbi.nlm.nih.gov/pubmed/24163350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1313029110
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi