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‘Living’ PEGylation on gold nanoparticles to optimize cancer cell uptake by controlling targeting ligand and charge densities
We report and demonstrate biomedical applications of a new technique – ‘living’ PEGylation – that allows control of the density and composition of heterobifunctional PEG (HS-PEG-R) on gold nanoparticles (AuNPs). We first establish ‘living’ PEGylation by incubating HS-PEG(5000)-COOH with AuNPs (~20 n...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3831850/ https://ncbi.nlm.nih.gov/pubmed/23940104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/0957-4484/24/35/355101 |
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