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‘Living’ PEGylation on gold nanoparticles to optimize cancer cell uptake by controlling targeting ligand and charge densities

We report and demonstrate biomedical applications of a new technique – ‘living’ PEGylation – that allows control of the density and composition of heterobifunctional PEG (HS-PEG-R) on gold nanoparticles (AuNPs). We first establish ‘living’ PEGylation by incubating HS-PEG(5000)-COOH with AuNPs (~20 n...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Chen, Hongwei, Paholak, Hayley, Ito, Masayuki, Sansanaphongpricha, Kanokwan, Qian, Wei, Che, Yong, Sun, Duxin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3831850/
https://ncbi.nlm.nih.gov/pubmed/23940104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/0957-4484/24/35/355101
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