Size- and charge-dependent non-specific uptake of PEGylated nanoparticles by macrophages

The assessment of macrophage response to nanoparticles is a central component in the evaluation of new nanoparticle designs for future in vivo application. This work investigates which feature, nanoparticle size or charge, is more predictive of non-specific uptake of nanoparticles by macrophages. Th...

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Bibliographic Details
Main Authors: Yu, Shann S, Lau, Cheryl M, Thomas, Susan N, Jerome, W Gray, Maron, David J, Dickerson, James H, Hubbell, Jeffrey A, Giorgio, Todd D
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2012
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3284223/
https://ncbi.nlm.nih.gov/pubmed/22359457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S28531
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