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Depleting tumor-associated Tregs via nanoparticle-mediated hyperthermia to enhance anti-CTLA-4 immunotherapy
AIM: We aim to demonstrate that a local nanoparticle-mediated hyperthermia can effectively eliminate tumor-associated Tregs and thereby boost checkpoint blockade-based immunotherapy. MATERIALS & METHODS: Photothermal therapy (PTT), mediated with systemically administered stealthy iron-oxide nano...
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| Izdano u: | Nanomedicine (Lond) |
|---|---|
| Glavni autori: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Future Medicine Ltd
2019
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7132783/ https://ncbi.nlm.nih.gov/pubmed/31868112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nnm-2019-0190 |
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