Φορτώνει......
Binding Mode Characterization of 6α- and 6β-N-Heterocyclic Substituted Naltrexamine Derivatives via Docking in Opioid Receptor Crystal Structures and Site-directed Mutagenesis Studies: Application of the “Message–Address” Concept in Development of Mu Opioid Receptor Selective Antagonists
Highly selective opioid receptor antagonists are essential pharmacological probes in opioid receptor structural characterization and opioid agonist functional studies. Currently, there is no highly selective, non-peptidyl and reversible mu opioid receptor antagonist available. Among a series of nalt...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2013
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3831368/ https://ncbi.nlm.nih.gov/pubmed/24055076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.08.042 |
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