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Contrasting Effects of Cyclosporine and Rapamycin in De Novo Generation of Alloantigen-Specific Regulatory T Cells

The outcome of T-cell-mediated responses, immunity or tolerance, critically depends on the balance of cytopathic versus regulatory T (T(reg)) cells. In the creation of stable tolerance to MHC incompatible allografts, reducing the unusually large mass of donorreactive cytopathic T effector (T(eff)) c...

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Detalhes bibliográficos
Main Authors: Gao, W., Lu, Y., Essawy, B. El, Oukka, M., Kuchroo, V.K., Strom, T.B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3831357/
https://ncbi.nlm.nih.gov/pubmed/17511761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2007.01842.x
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