iPSC-Derived Regulatory Dendritic Cells Inhibit Allograft Rejection by Generating Alloantigen-Specific Regulatory T Cells

Regulatory dendritic cell (DCregs)-based immunotherapy is a potential therapeutic tool for transplant rejection. We generated DCregs from murine induced pluripotent stem cells (iPSCs), which could remain in a “stable immature stage” even under strong stimulation. Harnessing this characteristic, we h...

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Pubblicato in:Stem Cell Reports
Autori principali: Cai, Songjie, Hou, Jiangang, Fujino, Masayuki, Zhang, Qi, Ichimaru, Naotsugu, Takahara, Shiro, Araki, Ryoko, Lu, Lina, Chen, Ji-Mei, Zhuang, Jian, Zhu, Ping, Li, Xiao-Kang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5425686/
https://ncbi.nlm.nih.gov/pubmed/28434942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.03.020
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