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Lovastatin inhibits brain endothelial cell Rho-mediated lymphocyte migration and attenuates experimental autoimmune encephalomyelitis
Neuroinflammatory diseases, such as multiple sclerosis (MS), result from aberrant leucocyte traffic into the central nervous system (CNS). To breach the specialized blood-brain barrier, activated leucocytes interact with CNS endothelial cells (EC) and activate a CD54-mediated signaling pathway contr...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2003
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3831156/ https://ncbi.nlm.nih.gov/pubmed/12626426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.02-1014fje |
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