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Identifying rare variants associated with complex traits via sequencing

Although genome-wide association studies have been successful in detecting associations with common variants, there is currently an increasing interest in identifying low frequency and rare variants associated with complex traits. Next-generation sequencing technologies make it feasible to survey th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Li, Bingshan, Liu, Dajiang J., Leal, Suzanne M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3830981/
https://ncbi.nlm.nih.gov/pubmed/23853079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/0471142905.hg0126s78
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