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Discovery of Rare Variants via Sequencing: Implications for the Design of Complex Trait Association Studies

There is strong evidence that rare variants are involved in complex disease etiology. The first step in implicating rare variants in disease etiology is their identification through sequencing in both randomly ascertained samples (e.g., the 1,000 Genomes Project) and samples ascertained according to...

詳細記述

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書誌詳細
主要な著者: Li, Bingshan, Leal, Suzanne M.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674213/
https://ncbi.nlm.nih.gov/pubmed/19436704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000481
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