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Methods for Detecting Associations with Rare Variants for Common Diseases: Application to Analysis of Sequence Data
Although whole-genome association studies using tagSNPs are a powerful approach for detecting common variants, they are underpowered for detecting associations with rare variants. Recent studies have demonstrated that common diseases can be due to functional variants with a wide spectrum of allele f...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2842185/ https://ncbi.nlm.nih.gov/pubmed/18691683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2008.06.024 |
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