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A Unified Method for Detecting Secondary Trait Associations with Rare Variants: Application to Sequence Data
Next-generation sequencing has made possible the detection of rare variant (RV) associations with quantitative traits (QT). Due to high sequencing cost, many studies can only sequence a modest number of selected samples with extreme QT. Therefore association testing in individual studies can be unde...
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| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Public Library of Science
2012
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3499373/ https://ncbi.nlm.nih.gov/pubmed/23166519 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003075 |
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