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Quantifying Additive Interactions of the Osmolyte Proline with Individual Functional Groups of Proteins: Comparisons with Urea and Glycine Betaine, Interpretation of m-Values

To quantify interactions of the osmolyte L-proline with protein functional groups and predict its effects on protein processes, we use vapor pressure osmometry to determine chemical potential derivatives dµ(2)/dm(3) = µ(23) quantifying preferential interactions of proline (component 3) with 21 solut...

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Autors principals: Diehl, Roger C., Guinn, Emily J., Capp, Michael W., Tsodikov, Oleg V., Record, M. Thomas
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3830607/
https://ncbi.nlm.nih.gov/pubmed/23909383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400683y
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