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Increased HO-1 Levels Ameliorate Fatty Liver Development Through a Reduction of Heme and Recruitment of FGF21
OBJECTIVE: Obese leptin deficient (ob/ob) mice are a model of adiposity that displays increased levels of fat, glucose and liver lipids. Our hypothesis is that HO-1 overexpression ameliorates fatty liver development. DESIGN AND METHODS: Obese mice were administered cobalt protoporphyrin (CoPP) and s...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3830593/ https://ncbi.nlm.nih.gov/pubmed/23839791 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/oby.20559 |
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