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Identification of a Secreted Casein Kinase 1 in Leishmania donovani: Effect of Protein over Expression on Parasite Growth and Virulence

Casein kinase 1 (CK1) plays an important role in eukaryotic signaling pathways, and their substrates include key regulatory proteins involved in cell differentiation, proliferation and chromosome segregation. The Leishmania genome encodes six potential CK1 isoforms, of which five have orthologs in o...

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Autors principals: Dan-Goor, Mary, Nasereddin, Abedelmajeed, Jaber, Hanan, Jaffe, Charles L.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829951/
https://ncbi.nlm.nih.gov/pubmed/24260187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079287
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