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Identification of a Secreted Casein Kinase 1 in Leishmania donovani: Effect of Protein over Expression on Parasite Growth and Virulence

Casein kinase 1 (CK1) plays an important role in eukaryotic signaling pathways, and their substrates include key regulatory proteins involved in cell differentiation, proliferation and chromosome segregation. The Leishmania genome encodes six potential CK1 isoforms, of which five have orthologs in o...

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Hlavní autoři: Dan-Goor, Mary, Nasereddin, Abedelmajeed, Jaber, Hanan, Jaffe, Charles L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829951/
https://ncbi.nlm.nih.gov/pubmed/24260187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079287
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