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Identification of a Secreted Casein Kinase 1 in Leishmania donovani: Effect of Protein over Expression on Parasite Growth and Virulence

Casein kinase 1 (CK1) plays an important role in eukaryotic signaling pathways, and their substrates include key regulatory proteins involved in cell differentiation, proliferation and chromosome segregation. The Leishmania genome encodes six potential CK1 isoforms, of which five have orthologs in o...

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Detalhes bibliográficos
Main Authors: Dan-Goor, Mary, Nasereddin, Abedelmajeed, Jaber, Hanan, Jaffe, Charles L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829951/
https://ncbi.nlm.nih.gov/pubmed/24260187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079287
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