Diet Induced Mild Hypercholesterolemia in Pigs: Local and Systemic Inflammation, Effects on Vascular Injury – Rescue by High-Dose Statin Treatment

OBJECTIVE: The aim of the present study was to comprehensively evaluate systemic and local inflammation as well as progression of vascular inflammation in normal and mechanically injured vessels in a large animal model of mild hypercholesterolemia. Our aim was also to test the effect of high-dose st...

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Główni autorzy: Busnelli, Marco, Manzini, Stefano, Froio, Alberto, Vargiolu, Alessia, Cerrito, Maria Grazia, Smolenski, Ryszard T., Giunti, Massimo, Cinti, Alessandro, Zannoni, Augusta, Leone, Biagio Eugenio, Forni, Monica, Bacci, Maria Laura, Biasi, Giorgio Maria, Giovannoni, Roberto, Lavitrano, Marialuisa
Format: Artigo
Język:Inglês
Wydane: Public Library of Science 2013
Hasła przedmiotowe:
Research Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829827/
https://ncbi.nlm.nih.gov/pubmed/24260430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080588
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