Unexpected frequency of genomic alterations in histologically normal colonic tissue from colon cancer patients

As shown by genomic studies, colorectal cancer (CRC) is a highly heterogeneous disease, where copy number alterations (CNAs) may greatly vary among different patients. To explore whether CNAs may be present also in histologically normal tissues from patients affected by CRC, we performed CGH + SNP M...

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Detalhes bibliográficos
Publicado no:Tumour Biol
Main Authors: Conconi, Donatella, Redaelli, Serena, Bovo, Giorgio, Leone, Biagio Eugenio, Filippi, Emanuela, Ambrosiani, Luciana, Cerrito, Maria Grazia, Grassilli, Emanuela, Giovannoni, Roberto, Dalprà, Leda, Lavitrano, Marialuisa
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5097093/
https://ncbi.nlm.nih.gov/pubmed/27481518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13277-016-5181-0
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