Genetically modified pigs produced with a nonviral episomal vector

Genetic modification of cells and animals is an invaluable tool for biotechnology and biomedicine. Currently, integrating vectors are used for this purpose. These vectors, however, may lead to insertional mutagenesis and variable transgene expression and can undergo silencing. Scaffold/matrix attach...

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Bibliografiske detaljer
Main Authors: Manzini, Stefano, Vargiolu, Alessia, Stehle, Isa M, Bacci, Maria Laura, Cerrito, Maria Grazia, Giovannoni, Roberto, Zannoni, Augusta, Bianco, Maria Rosaria, Forni, Monica, Donini, Pierluigi, Papa, Michele, Lipps, Hans J, Lavitrano, Marialuisa
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2006
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635978/
https://ncbi.nlm.nih.gov/pubmed/17101993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604938103
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