Development of small molecule inhibitors targeting adipose triglyceride lipase

Adipose triglyceride lipase (ATGL) is rate-limiting in the mobilization of fatty acids from cellular triglyceride stores. This central role in lipolysis marks ATGL as interesting pharmacological target since deregulated fatty acid metabolism is closely linked to dyslipidemic and metabolic disorders....

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Main Authors: Mayer, Nicole, Schweiger, Martina, Romauch, Matthias, Grabner, Gernot F., Eichmann, Thomas O., Fuchs, Elisabeth, Ivkovic, Jakov, Heier, Christoph, Mrak, Irina, Lass, Achim, Höfler, Gerald, Fledelius, Christian, Zechner, Rudolf, Zimmermann, Robert, Breinbauer, Rolf
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829776/
https://ncbi.nlm.nih.gov/pubmed/24096302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1359
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