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Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice
Elevated circulating fatty acids (FAs) contribute to the development of obesity-associated metabolic complications such as insulin resistance (IR) and non-alcoholic fatty liver disease (NAFLD). Hence, reducing adipose tissue lipolysis to diminish the mobilization of FAs and lower their respective pl...
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Pubblicato in: | Nat Commun |
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Autori principali: | , , , , , , , , , , , , , , , , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
Nature Publishing Group
2017
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5364409/ https://ncbi.nlm.nih.gov/pubmed/28327588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14859 |
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