Structure–activity studies in the development of a hydrazone based inhibitor of adipose-triglyceride lipase (ATGL)

Adipose triglyceride lipase (ATGL) catalyzes the degradation of cellular triacylglycerol stores and strongly determines the concentration of circulating fatty acids (FAs). High serum FA levels are causally linked to the development of insulin resistance and impaired glucose tolerance, which eventual...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Bioorg Med Chem
Prif Awduron: Mayer, Nicole, Schweiger, Martina, Melcher, Michaela-Christina, Fledelius, Christian, Zechner, Rudolf, Zimmermann, Robert, Breinbauer, Rolf
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier Science 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457358/
https://ncbi.nlm.nih.gov/pubmed/25778769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2015.02.051
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