Structure–activity studies in the development of a hydrazone based inhibitor of adipose-triglyceride lipase (ATGL)

Adipose triglyceride lipase (ATGL) catalyzes the degradation of cellular triacylglycerol stores and strongly determines the concentration of circulating fatty acids (FAs). High serum FA levels are causally linked to the development of insulin resistance and impaired glucose tolerance, which eventual...

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Detaylı Bibliyografya
Yayımlandı:Bioorg Med Chem
Asıl Yazarlar: Mayer, Nicole, Schweiger, Martina, Melcher, Michaela-Christina, Fledelius, Christian, Zechner, Rudolf, Zimmermann, Robert, Breinbauer, Rolf
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier Science 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457358/
https://ncbi.nlm.nih.gov/pubmed/25778769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2015.02.051
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