Structure–activity studies in the development of a hydrazone based inhibitor of adipose-triglyceride lipase (ATGL)

Adipose triglyceride lipase (ATGL) catalyzes the degradation of cellular triacylglycerol stores and strongly determines the concentration of circulating fatty acids (FAs). High serum FA levels are causally linked to the development of insulin resistance and impaired glucose tolerance, which eventual...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Bioorg Med Chem
Main Authors: Mayer, Nicole, Schweiger, Martina, Melcher, Michaela-Christina, Fledelius, Christian, Zechner, Rudolf, Zimmermann, Robert, Breinbauer, Rolf
Format: Artigo
Jezik:Inglês
Izdano: Elsevier Science 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457358/
https://ncbi.nlm.nih.gov/pubmed/25778769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2015.02.051
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki