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Development of small molecule inhibitors targeting adipose triglyceride lipase
Adipose triglyceride lipase (ATGL) is rate-limiting in the mobilization of fatty acids from cellular triglyceride stores. This central role in lipolysis marks ATGL as interesting pharmacological target since deregulated fatty acid metabolism is closely linked to dyslipidemic and metabolic disorders....
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| Hauptverfasser: | , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3829776/ https://ncbi.nlm.nih.gov/pubmed/24096302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1359 |
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