A Peptide Derived from G(0)/G(1) Switch Gene 2 Acts as Noncompetitive Inhibitor of Adipose Triglyceride Lipase

The protein G(0)/G(1) switch gene 2 (G0S2) is a small basic protein that functions as an endogenous inhibitor of adipose triglyceride lipase (ATGL), a key enzyme in intracellular lipolysis. In this study, we identified a short sequence covering residues Lys-20 to Ala-52 in G0S2 that is still fully c...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Cerk, Ines K., Salzburger, Barbara, Boeszoermenyi, Andras, Heier, Christoph, Pillip, Christoph, Romauch, Matthias, Schweiger, Martina, Cornaciu, Irina, Lass, Achim, Zimmermann, Robert, Zechner, Rudolf, Oberer, Monika
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2014
Subjects:
Lipids
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239610/
https://ncbi.nlm.nih.gov/pubmed/25258314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.602599
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