Development of small molecule inhibitors targeting adipose triglyceride lipase

Adipose triglyceride lipase (ATGL) is rate-limiting in the mobilization of fatty acids from cellular triglyceride stores. This central role in lipolysis marks ATGL as interesting pharmacological target since deregulated fatty acid metabolism is closely linked to dyslipidemic and metabolic disorders....

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Hlavní autoři: Mayer, Nicole, Schweiger, Martina, Romauch, Matthias, Grabner, Gernot F., Eichmann, Thomas O., Fuchs, Elisabeth, Ivkovic, Jakov, Heier, Christoph, Mrak, Irina, Lass, Achim, Höfler, Gerald, Fledelius, Christian, Zechner, Rudolf, Zimmermann, Robert, Breinbauer, Rolf
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829776/
https://ncbi.nlm.nih.gov/pubmed/24096302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1359
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