Histone H2A Ubiquitination Inhibits the Enzymatic Activity of H3 Lysine 36 Methyltransferases

Histone H3 lysine 27 (H3K27) methylation and H2A monoubiquitination (ubH2A) are two closely related histone modifications that regulate Polycomb silencing. Previous studies reported that H3K27 trimethylation (H3K27me3) rarely coexists with H3K36 di- or tri-methylation (H3K36me2/3) on the same histon...

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Bibliographische Detailangaben
Hauptverfasser: Yuan, Gang, Ma, Ben, Yuan, Wen, Zhang, Zhuqiang, Chen, Ping, Ding, Xiaojun, Feng, Li, Shen, Xiaohua, Chen, She, Li, Guohong, Zhu, Bing
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2013
Schlagworte:
Gene Regulation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829398/
https://ncbi.nlm.nih.gov/pubmed/24019522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.475996
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