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The Serine-threonine Kinase Inositol-requiring Enzyme 1α (IRE1α) Promotes IL-4 Production in T Helper Cells

The inositol-requiring enzyme 1α (IRE1α) is a serine-threonine kinase that plays crucial roles in activating the unfolded protein response. Studies suggest that IRE1α is activated during thymic T cell development and in effector CD8(+) T cells. However, its role in regulating T helper cell different...

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Detalhes bibliográficos
Main Authors: Kemp, Kyeorda L., Lin, Zhenghong, Zhao, Fang, Gao, Beixue, Song, Jianxun, Zhang, Kezhong, Fang, Deyu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829173/
https://ncbi.nlm.nih.gov/pubmed/24100031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.493171
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