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Inhibition of Telomerase Recruitment and Cancer Cell Death
Continued proliferation of human cells requires maintenance of telomere length, usually accomplished by telomerase. Telomerase is recruited to chromosome ends by interaction with a patch of amino acids (the TEL patch, for TPP1 glutamate (E) and leucine (L)-rich patch) on the surface of telomere prot...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3829164/ https://ncbi.nlm.nih.gov/pubmed/24097987 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.518175 |
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