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Axl/Gas6 pathway participates in human natural killer cell development by positively regulating FLT3 activation

Activation of the FMS-like tyrosine kinase 3 (FLT3) by its ligand, FLT3 ligand (FL), strongly augments development of natural killer (NK) cells from human CD34(+) hematopoietic progenitor cells (HPCs) in the presence of interleukin-15 (IL-15), compared to IL-15 alone. In this study, we observed that...

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Detalhes bibliográficos
Main Authors: Park, Il-Kyoo, Trotta, Rossana, Yu, Jianhua, Caligiuri, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829002/
https://ncbi.nlm.nih.gov/pubmed/23722894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201243116
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