Par-complex aPKC and Par3 cross-talk with innate immunity NF-κB pathway in epithelial cells

Components of the Par-complex, atypical PKC and Par3, have been found to be downregulated upon activation of NF-κB in intestinal epithelial cells. To determine their possible role in pro-inflammatory responses we transduced Caco-2 human colon carcinoma cells with constitutively active (ca) PKCι or a...

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Bibliographic Details
Main Authors: Forteza, Radia, Wald, Flavia A., Mashukova, Anastasia, Kozhekbaeva, Zhanna, Salas, Pedro J.
Format: Artigo
Language:Inglês
Published: The Company of Biologists 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828774/
https://ncbi.nlm.nih.gov/pubmed/24244864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20135918
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